منابع مشابه
Pns1300100 226..235
This review describes historical iodine deficiency in the UK, gives current information on dietary sources of iodine and summarises recent evidence of iodine deficiency and its association with child neurodevelopment. Iodine is required for the production of thyroid hormones that are needed for brain development, particularly during pregnancy. Iodine deficiency is a leading cause of preventable...
متن کاململحق العدد
یشتمل علی المباحث النّقدیّة: · نقد الکتب والمقالات · نقد النّقد · الترجمة · التّقریر الحوار و...
متن کاملDmd060046 217..226
5-[(2-Chloro-6-fluorophenyl)acetylamino]-3-(4-fluorophenyl)-4(4-pyrimidinyl)isoxazole (AKP-001) is a potent p38 mitogen-activated protein kinase inhibitor that is being developed to specifically target the intestines for the treatment of inflammatory bowel disease. According to the ante-drug concept, AKP-001 was designed to be metabolized to inactive forms via the first-pass metabolism to avoid...
متن کاملNpgrj_nn_1624 220..226
Two clearly opposing views exist on the function of alpha-fetoprotein (AFP), a fetal plasma protein that binds estrogens with high affinity, in the sexual differentiation of the rodent brain. AFP has been proposed to either prevent the entry of estrogens or to actively transport estrogens into the developing female brain. The availability of Afp mutant mice (Afp–/–) now finally allows us to res...
متن کاملC1lc20678h 219..226
In this work, we developed a microfluidic device for the imitation of drug metabolism in human liver and its cytotoxicity on cells. The integrated microfluidic device consists of three sections: (1) bioreactors containing poly(ethylene) glycol (PEG) hydrogel encapsulated human liver microsomes (HLMs); (2) cell culture chambers for cytotoxicity assay; and (3) integrated micro solid-phase extract...
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ژورنال
عنوان ژورنال: مجلة القراءة والمعرفة
سال: 2020
ISSN: 2735-3273
DOI: 10.21608/mrk.2020.111151